Hearing recovering using stem cells
To recover the hearing with the help of stem cells is Kelvin Kwan’s key mission in his practice. He is a lecturer at the department of neurobiology at Harvard Medical School, Boston.MA and he has been searching for a solution to this problem for many years.
More than 15% of the world's population suffers from hearing loss. The reasons of this fact may differ – it might be the age-related changes in the body, and the effect of noise, and genetic predisposition, as well as the use of ototoxic drugs. Many of us do not even realize that they lose their hearing until they purposefully visit the doctor for diagnosis. Sensor neural hearing loss is often caused by loss of hair cells in the inner ear. The search for the possibility of restoring such cells is handled by Kwan, the laboratory he works in is one of the few scientific centers that are working to restore hearing.
In theory everything looks simple enough: stem cells in the inner ear can be transformed into auditory neurons, but in reality, scientists have faced the problem - the auditory analyzer neurons derived from inner ear stem cells with the manipulation of the NEUROG1 gene divide too quickly, and this creates a risk of cancer. Kelvin Kwan found that histone chromatin proteins can control the process of cell division. Changes in chromatin with chemicals help to reduce unnecessary cell division. Today, the University of Rutgers laboratory in New Brunswick is developing technologies for realizing research іn vivo - in a living organism. Biotechnological innovation in stem cell therapy will help restore the hearing of millions of people around the world.